CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9538
Family Name Amyloid beta A4 protein and Luciferin 4-monooxygenase inhibitor 4-(1,3-Benzothiazol-2-yl)-N,N-dimethylaniline family
No. of Seeds 11 No. of Other Members 46
Family Centroid CFAMM00313283 Functional Category Bioactive with Natural Product
Superfamily Acetylcholinesterase and Histamine H3 receptor Binder Superfamily
Class Class 3184

Cousin Family NamesSeedsMembers
AP endonuclease APE1 Inhibitor 1,3-bis(1,3-benzothiazol-2-ylth... 1 12
Prothrombin Inhibitor Benzothiazole Family 1 29
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-amin... 5 24
Aldose reductase Inhibitor Lidorestat Family 16 27
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Histamine H3 receptor Ligand ST-1025 Family 2 22
Translocator protein Inhibitor 5-phenyl-6-thia-10b-aza-benzo[e... 1 2
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Phosphoribosylaminoimidazolecarboxamide formyltransferase Inhi... 1 13
Metabotropic glutamate receptor 5 Ligand 3-(2-methylbenzo[d]th... 1 22
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-(2,6... 5 9
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 20
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 14
Mitogen-activated protein kinase 1 and Retinal dehydrogenase 1... 1 5
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 3 7
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 8 6
D(4) dopamine receptor ligand SureCN8706945 family 4 10
Sodium-dependent serotonin transporter and D(4) dopamine recep... 2 4
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 2 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03VWQ9 family 3 5
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 1 1
5-hydroxytryptamine receptor 1A and Alpha-2C adrenergic recept... 2 2
Amyloid beta A4 protein inhibitor SureCN2465837 family 4 2
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[2-(1,3-benzothia... 1 3
Microtubule-associated protein tau inhibitor CHEMBL1789430 family 1 1
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 2 1
Sphingosine 1-phosphate receptor 4 and 3-hydroxyacyl-CoA dehyd... 1 1
(E)-2-(1,3-benzothiazol-2-yl)-3-thiophen-2-ylprop-2-enenitrile... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396292 CHEMBL330529 Bioactive SureCN178156
CFAMM00396291 CHEMBL92802 Bioactive AGN-PC-00GUV6
CFAMM00396336 CHEMBL1944953 Bioactive 4-[(E)-2-(5-fluoro-3-methyl-1,3-benzothiazol-3-ium-2-yl)ethenyl]-N,N-dimethylaniline
CFAMM00396335 CHEMBL93109 Bioactive 92-36-4
CFAMM00396318 CHEMBL55380 Bioactive SureCN1726866
CFAMM00396334 CHEMBL1944955 Bioactive 4-[(E)-2-(3,6-dimethyl-1,3-benzothiazol-3-ium-2-yl)ethenyl]-N,N-dimethylaniline
CFAMM00396317 CHEMBL370968 Bioactive 4-[(E)-2-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)ethenyl]-N,N-dimethylaniline
CFAMM00396333 CHEMBL1944954 Bioactive 4-[(E)-2-(3,5-dimethyl-1,3-benzothiazol-3-ium-2-yl)ethenyl]-N,N-dimethylaniline
CFAMM00396316 CHEMBL370967 Bioactive N,N-dimethyl-4-[(E)-2-(3-methyl-1,3-benzothiazol-3-ium-2-yl)ethenyl]aniline
CFAMM00396283 CHEMBL58092 Bioactive SureCN14075963

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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