CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9541
Family Name Proto-oncogene tyrosine-protein kinase Src inhibitor AGN-PC-074CCS family
No. of Seeds 17 No. of Other Members 9
Family Centroid CFAMM00396396 Functional Category Bioactive
Superfamily D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A Binder Superfamily 4
Class Class 2018

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor and Receptor tyrosine-protein... 16 89
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 67 130
Epidermal growth factor receptor and Abelson tyrosine-protein ... 6 3
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS94Q ... 6 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN4... 9 2
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 1 0


External ID

Functional Category

Molecule Name

CFAMM00396408 CHEMBL431136 Bioactive AGN-PC-074CCB
CFAMM00396388 CHEMBL59786 Bioactive 7-thienyl-3-quinolinecarbonitrile 8
CFAMM00396394 CHEMBL194664 Bioactive AC1NS8AB
CFAMM00396407 CHEMBL59850 Bioactive 7-thienyl-3-quinolinecarbonitrile 9
CFAMM00396400 CHEMBL418693 Bioactive 7-thienyl-3-quinolinecarbonitrile 10
CFAMM00396399 CHEMBL410251 Bioactive SureCN4904402
CFAMM00396392 CHEMBL194503 Bioactive AC1NS89T
CFAMM00396404 CHEMBL294137 Bioactive AGN-PC-074CDA
CFAMM00396390 CHEMBL418652 Bioactive 7-thienyl-3-quinolinecarbonitrile 15
CFAMM00396403 CHEMBL363575 Bioactive SureCN4904386
CFAMM00396396 CHEMBL304471 Bioactive AGN-PC-074CCS
CFAMM00396402 CHEMBL195419 Bioactive AC1NS88Z
CFAMM00396395 CHEMBL370473 Bioactive AC1NS89E

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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