CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9556
Family Name Melanin-concentrating hormone receptor 1 ligand 6-methoxy-4-[[1-[(E)-3-phenylprop-2-enyl]piperidin-4-yl]amino]chromen-2-one family
No. of Seeds 2 No. of Other Members 15
Family Centroid CFAMM00396485 Functional Category Bioactive with Natural Product
Superfamily Survival motor neuron protein and ATP-dependent DNA helicase Q1 Binder Superfamily
Class Class 93

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
Sigma non-opioid intracellular receptor 1 ligand BAS 04057753 ... 5 8
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26


External ID

Functional Category

Molecule Name

CFAMM00396485 CHEMBL194576 Bioactive 6-methoxy-4-[[1-[(E)-3-phenylprop-2-enyl]piperidin-4-yl]amino]chromen-2-one
CFAMM00396498 CHEMBL196208 Bioactive 4-[[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]amino]-6-methoxychromen-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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