CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9564
Family Name D(4) dopamine receptor ligand SureCN8706945 family
No. of Seeds 4 No. of Other Members 10
Family Centroid CFAMM00396540 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Microtubule-associated protein tau Binder Superfamily 7
Class Class 2719

Cousin Family NamesSeedsMembers
Aldose reductase Inhibitor Lidorestat Family 16 27
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 12
Histamine H3 receptor Ligand ST-1025 Family 2 22
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Metabotropic glutamate receptor 5 Ligand 3-(2-methylbenzo[d]th... 1 22
Squalene synthase inhibitor SureCN7761201 family 2 14
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-(2,6... 5 9
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 20
Amyloid beta A4 protein and Luciferin 4-monooxygenase inhibito... 11 46
Sodium-dependent serotonin transporter and D(4) dopamine recep... 2 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
C-C chemokine receptor type 3 and C-C chemokine receptor type ... 1 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 1
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03VWQ9 family 3 5
5-hydroxytryptamine receptor 1A and Alpha-2C adrenergic recept... 2 2
Amyloid beta A4 protein inhibitor SureCN2465837 family 4 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[2-(1,3-benzothia... 1 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(1,... 1 0
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00396540 CHEMBL306265 Bioactive SureCN8706945
CFAMM00396545 CHEMBL1945931 Bioactive 4-[(E)-2-(5-chloro-3-methyl-1,3-benzothiazol-3-ium-2-yl)ethenyl]-N,N-dimethylaniline

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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