CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9580
Family Name 5-hydroxytryptamine receptor 1A ligand oxalic acid;(1R,5S)-5-[(2-phenoxyethylamino)methyl]-2,2-diphenylcyclopentan-1-ol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00396620 Functional Category Bioactive
Superfamily Voltage-gated sodium channel Ligand SB-221420-A Superfamily
Class Class 142

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
Muscarinic acetylcholine receptor M3 Ligand Darifenacin Family 3 17
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Extracellular calcium-sensing receptor and Potassium voltage-g... 3 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 2 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 1 0
Sodium-dependent noradrenaline transporter and Cytochrome P450... 11 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396620 CHEMBL1946784 Bioactive oxalic acid;(1R,5S)-5-[(2-phenoxyethylamino)methyl]-2,2-diphenylcyclopentan-1-ol
CFAMM00396619 CHEMBL1946785 Bioactive oxalic acid;(1R,5R)-5-[(2-phenoxyethylamino)methyl]-2,2-diphenylcyclopentan-1-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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