CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9591
Family Name Mitogen-activated protein kinase 13 and Mitogen-activated protein kinase 12 inhibitor AGN-PC-00BQJZ family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00396685 Functional Category Bioactive
Superfamily Ribosomal protein S6 kinase alpha-3 and Mitogen-activated protein kinase 13 Binder Superfamily
Class Class 144

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Tyrosine-protein kinase BTK Inhibitor CC-292 Family 6 10
JAK Inhibitor Momelotinib Family 33 83
XL-888 family 16 85
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
Mitogen-activated protein kinase 14 inhibitor AGN-PC-04UPTJ fa... 3 20
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Metabotropic glutamate receptor 2 ligand AGN-PC-09QJ9P family 2 7
Hepatocyte growth factor receptor and Insulin receptor ligand ... 4 15
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Mitogen-activated protein kinase 14 inhibitor SureCN3305171 fa... 1 0
Mitogen-activated protein kinase 14 inhibitor ethyl N-[4-[5-(m... 5 2
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 0
Tyrosine-protein kinase Lck and Mitogen-activated protein kina... 2 7
Casein kinase II subunit alpha inhibitor CHEMBL401945 family 12 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Transient receptor potential cation channel subfamily V member... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396690 CHEMBL274257 Bioactive AGN-PC-00CRC8
CFAMM00396689 CHEMBL194813 Bioactive 3-[[5-cyano-6-[2,2-dimethylpropyl(methyl)amino]-2-(methylamino)pyrimidin-4-yl]amino]-N-methoxy-4-methylbenzamide
CFAMM00396688 CHEMBL363643 Bioactive AGN-PC-00DHJJ
CFAMM00396687 CHEMBL383137 Bioactive AGN-PC-00ATV8
CFAMM00396686 CHEMBL382954 Bioactive AGN-PC-00AIXU
CFAMM00396692 CHEMBL196741 Bioactive 5-Cyanopyrimidine Derivative 2
CFAMM00396685 CHEMBL195532 Bioactive AGN-PC-00BQJZ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543