CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9607
Family Name Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 inhibitor 2-[6-fluoro-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic acid family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00187103 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Prostaglandin G/H synthase 2 Binder Superfamily
Class Class 643

Cousin Family NamesSeedsMembers
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Substance-P receptor Ligand GSK424887 Family 8 184
Sodium channel Ligand GSK1014802 Family 4 92
Indeglitazar family 3 39
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... 4 25
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Endothelin B receptor Ligand IRL-2500 Family 34 87
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 6
Prostaglandin D2 receptor 2 ligand 2-[1-(4-benzamidobenzoyl)is... 4 9
D-amino-acid oxidase inhibitor SureCN679780 family 1 5
Insulin receptor ligand 2,5-dihydroxy-3-(1H-indol-3-yl)-6-phen... 1 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 48


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396802 CHEMBL1950016 Bioactive 2-[6-chloro-5-fluoro-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27056 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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