CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9613
Family Name Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]fluoren-9-one family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00396860 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit alpha-7 Binder Superfamily 2
Class Class 2572

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Levobunolol Family 6 133
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Histamine H3 receptor Ligand A-349821 Family 49 228
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 18 13
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 8
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 2 5
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
Estrogen receptor beta and Estrogen receptor ligand AGN-PC-074... 5 4
Acetylcholinesterase and Butyrylcholinesterase inhibitor 2-[4-... 3 2
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 1 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00S... 1 1
Multidrug resistance protein 1 inhibitor 1-[4-[(2R)-2-hydroxy-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396861 CHEMBL1950158 Bioactive 2-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]fluoren-9-one
CFAMM00396860 CHEMBL1950150 Bioactive 2,7-bis[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]fluoren-9-one
CFAMM00396859 CHEMBL1950151 Bioactive 2,7-bis[[(3S)-1-azabicyclo[2.2.2]octan-3-yl]oxy]fluoren-9-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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