CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9615
Family Name Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl)fluoren-9-one family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00396867 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit alpha-7 and Histamine H3 receptor Binder Superfamily
Class Class 4461

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Poly [ADP-ribose] polymerase 1 Inhibitor 8-amino-6h,11h-indeno... 3 9
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 4
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BLN ... 2 1
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 2 1
Histamine H3 receptor ligand SureCN3058680 family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396868 CHEMBL1950154 Bioactive 2,7-bis(2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)fluoren-9-one
CFAMM00396867 CHEMBL1950155 Bioactive 2,7-bis(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl)fluoren-9-one
CFAMM00396869 CHEMBL1950172 Bioactive 2-amino-7-(2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)fluoren-9-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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