CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM962
Family Name Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha ligand AGN-PC-07ZEOD family
No. of Seeds 10 No. of Other Members 2
Family Centroid CFAMM00317973 Functional Category Bioactive
Superfamily Translocator protein and 5-hydroxytryptamine receptor 2A Binder Superfamily
Class Class 433

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Platelet-derived growth factor receptor alpha and Platelet-der... 5 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
NF-kappa-B Inhibitor 9-chloro-5h-6-thia-4,5-diaza-chrysene 6,6... 3 27
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Prostaglandin G/H synthase 1 Inhibitor 1-(4-aminosulfonylpheny... 3 18
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Prostaglandin G/H synthase 2 Inhibitor 2-(4-(methylsulfonyl)ph... 7 33
C-C chemokine receptor type 5 ligand AC1LAJBP family 2 6
Motilin receptor and Cytochrome P450 2D6 ligand 7-[[6-(4-chlor... 2 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-07ZA0N family 1 3
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
Cannabinoid receptor 2 ligand 1,1,1-trifluoro-N-[(2S)-6-(1-pyr... 2 1
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 8
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 5 10
5-hydroxytryptamine receptor 6 ligand AGN-PC-09QKIN family 2 9
Substance-K receptor and Cytochrome P450 2D6 ligand 158848-32-... 4 4
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 4-[2-(... 2 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
5-hydroxytryptamine receptor 6 and Muscarinic acetylcholine re... 7 3
5-hydroxytryptamine receptor 6 ligand 1-(4-chlorophenyl)sulfon... 8 4
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 12 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 4 0
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 5 2
Prostaglandin G/H synthase 2 inhibitor SureCN6345015 family 6 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Oxysterols receptor LXR-beta ligand SureCN3491581 family 1 2
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 1 0
Metabotropic glutamate receptor 5 and Cytochrome P450 1A2 liga... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00317977 CHEMBL1097158 Bioactive AGN-PC-07ZES8
CFAMM00317976 CHEMBL1097159 Bioactive AGN-PC-07ZES9
CFAMM00317975 CHEMBL1098401 Bioactive AGN-PC-07ZEPR
CFAMM00317981 CHEMBL1096719 Bioactive AGN-PC-07ZEPU
CFAMM00317974 CHEMBL1098403 Bioactive AGN-PC-07ZEPT
CFAMM00317973 CHEMBL1094741 Bioactive AGN-PC-07ZEOD
CFAMM00317978 CHEMBL1097799 Bioactive AGN-PC-07ZER7

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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