CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9625
Family Name Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-PC-04TKGG family
No. of Seeds 14 No. of Other Members 1
Family Centroid CFAMM00351489 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and C-C chemokine receptor type 5 Binder Superfamily
Class Class 173

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Neuromedin-K receptor Ligand SB222200 Family 17 235
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Setipiprant family 5 118
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Potassium voltage-gated channel subfamily H member 2 Ligand E-... 1 4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Transient receptor potential cation channel subfamily V member... 6 23
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
Mineralocorticoid receptor and Androgen receptor Ligand WAY-25... 10 26
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Endothelin B receptor Ligand IRL-2500 Family 34 87
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Metabotropic glutamate receptor 5 Ligand 1-(3-(2-methylquinoli... 2 12
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 7 58
Sodium-dependent serotonin transporter and Sodium-dependent do... 10 2
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 1 11
Histamine H3 receptor ligand AGN-PC-04YWRD family 5 13
C-C chemokine receptor type 5 and C-C motif chemokine 5 ligand... 1 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Thyroid hormone receptor beta and Microtubule-associated prote... 1 8
Disintegrin and metalloproteinase domain-containing protein 17... 4 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 5 8
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Translocator protein inhibitor AGN-PC-08WI0V family 1 0
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 4 2
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9SVV family 2 12
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Translocator protein inhibitor N,N-diethyl-11-(2-fluoroethyl)-... 14 9
Cannabinoid receptor 1 ligand (2-cyclopentyl-5-prop-2-enyl-3,4... 3 8
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 3 5
Cannabinoid receptor 1 ligand N-[2-(cyclopropylamino)-2-oxoeth... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547533 f... 3 2
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Motilin receptor ligand SureCN2768052 family 3 0
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 2 2
Substance-P receptor ligand AGN-PC-004REJ family 3 0
Platelet-activating factor receptor ligand (4R)-N-(3-benzoylph... 2 1
Substance-P receptor and Substance-K receptor ligand N-methyl-... 2 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Histamine H3 receptor ligand SureCN3542210 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396904 CHEMBL250607 Bioactive [4-ethylsulfonyl-2-(oxan-2-yl)-1,3-dihydropyrrolo[3,4-b]indol-7-yl]-(4-methylpiperidin-1-yl)methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

41337 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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