CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9633
Family Name Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-(4-methoxyanilino)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile family
No. of Seeds 1 No. of Other Members 26
Family Centroid CFAMM00396950 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Prelamin-A/C Binder Superfamily 10
Class Class 2070

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Histone deacetylase 1 Inhibitor 7-(4-(dimethylamino)phenoxy)-n... 2 1
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 11 13
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 2 18
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-087THW family 1 0
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Capsid scaffolding protein inhibitor AC1LAC6N family 2 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor [(... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396950 CHEMBL195063 Bioactive (2S)-1-[(2S,4S)-4-(4-methoxyanilino)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27634 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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