CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9634
Family Name Histamine H3 receptor ligand 6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-methylpyridazin-3-one family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00396959 Functional Category Bioactive
Superfamily Histamine H3 receptor and Niemann-Pick C1 protein Binder Superfamily
Class Class 3127

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A ligand 6-methyl-5-[4-[3-[(2R)-... 12 3
Histamine H3 receptor ligand 3-[4-[3-[(2R)-2-methylpyrrolidin-... 1 5


External ID

Functional Category

Molecule Name

CFAMM00396961 CHEMBL1950740 Bioactive 6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-propan-2-ylpyridazin-3-one
CFAMM00396960 CHEMBL1950739 Bioactive 6-[6-(1-cyclopentylpiperidin-4-yl)oxypyridin-3-yl]-2-methylpyridazin-3-one
CFAMM00396959 CHEMBL1950738 Bioactive 6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-methylpyridazin-3-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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