CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9635
Family Name Histamine H3 receptor ligand (4R)-3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00396962 Functional Category Bioactive
Superfamily Histamine H3 receptor Binder Superfamily 6
Class Class 3665

Cousin Family NamesSeedsMembers
Irdabisant family 49 53
Histone deacetylase 2 and Histone deacetylase 3 inhibitor N'-h... 1 2
Histamine H3 receptor ligand 6-[3-chloro-4-[3-[(2R)-2-methylpy... 1 0
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand 3-methyl-1-[4-(3-piperidin-1-ylpr... 6 1
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 7 13
5-hydroxytryptamine receptor 3A ligand 5-[4-[3-(azepan-1-yl)pr... 2 0


External ID

Functional Category

Molecule Name

CFAMM00396964 CHEMBL1950743 Bioactive 3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-5,5-dimethyl-1,4-dihydropyridazin-6-one
CFAMM00396963 CHEMBL1950745 Bioactive 3-[4-(1-cyclobutylpiperidin-4-yl)oxy-3-fluorophenyl]-5,5-dimethyl-1,4-dihydropyridazin-6-one
CFAMM00396962 CHEMBL1950746 Bioactive (4R)-3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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