CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9664
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor AGN-PC-04SERD family
No. of Seeds 7 No. of Other Members 13
Family Centroid CFAMM00397095 Functional Category Bioactive with Natural Product
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-specific 3',5'-cyclic phosphodiesterase 4D Binder Superfamily
Class Class 928

Cousin Family NamesSeedsMembers
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Irdabisant family 49 53
cAMP-specific 3',5'-cyclic phosphodiesterase 4B Inhibitor Fila... 9 9
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Zard... 2 3
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA5P family 4 11
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA03 family 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
Histamine H3 receptor ligand 6-[3-chloro-4-[3-[(2R)-2-methylpy... 1 0
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand 3-methyl-1-[4-(3-piperidin-1-ylpr... 6 1
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
Histamine H3 receptor ligand (4R)-3-[4-(1-cyclobutylpiperidin-... 4 0
Beta-2 adrenergic receptor and cAMP-specific 3',5'-cyclic phos... 2 4
5-hydroxytryptamine receptor 3A ligand 5-[4-[3-(azepan-1-yl)pr... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and Sodium-dep... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor (4aS... 10 0
Poly [ADP-ribose] polymerase 1 inhibitor [3-[(4-oxo-3H-phthala... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397110 CHEMBL463431 Bioactive SureCN6484725
CFAMM00397095 CHEMBL314782 Bioactive AGN-PC-04SERD
CFAMM00397108 CHEMBL595039 Bioactive (4aS,8aR)-4-(3,4-dimethoxyphenyl)-2-[[4-[(dimethylamino)methyl]phenyl]methyl]-4a,5,8,8a-tetrahydrophthalazin-1-one
CFAMM00397100 CHEMBL430831 Bioactive AGN-PC-0BPYWE
CFAMM00397113 CHEMBL480988 Bioactive phthalazinone, 20
CFAMM00397104 CHEMBL81960 Bioactive AGN-PC-0BNQDM
CFAMM00397097 CHEMBL195155 Bioactive 6-(3,4-dimethoxyphenyl)-2-(5-phenylpentyl)pyridazin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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