CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9670
Family Name Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5 ligand CHEMBL1951659 family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00397171 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5 Binder Superfamily
Class Class 3795

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
Transient receptor potential cation channel subfamily V member... 1 17
Muscarinic acetylcholine receptor M4 Ligand VU10007 Family 2 17
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Metabotropic glutamate receptor 1 ligand AGN-PC-046KML family 7 40
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 13 37
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9TG5 family 11 10
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9S6C family 10 1
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9PTC family 4 1
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9T4A family 3 0
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9T4C family 1 0
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 2
Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2... 2 3
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 2 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 7 1
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Metabotropic glutamate receptor 1 ligand SureCN8238697 family 2 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... 4 4
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 1 0
Intercellular adhesion molecule 1 and E-selectin inhibitor Sur... 1 0
Gamma-aminobutyric acid receptor subunit alpha-2 and Gamma-ami... 6 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 2
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 1 4
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 1 1
Metabotropic glutamate receptor 5 ligand 2-(2-pyridin-3-ylethy... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397171 CHEMBL1951659 Bioactive CHEMBL1951659
CFAMM00397170 CHEMBL1951877 Bioactive CHEMBL1951877

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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