CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9674
Family Name Muscarinic acetylcholine receptor M2 and Muscarinic acetylcholine receptor M1 ligand AGN-PC-074H6X family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00273802 Functional Category Bioactive with Natural Product
Superfamily D(3) dopamine receptor Ligand GR-218231 Superfamily
Class Class 1431

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 15 129
Histamine H3 receptor Ligand A-349821 Family 49 228
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
D(3) dopamine receptor Ligand GR-218231 Family 4 17
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 13
Muscarinic acetylcholine receptor M2 ligand (2-chlorophenyl)-[... 7 3
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OX family 2 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074ITY family 16 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074ZZ3 family 11 1
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 9 4
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Muscarinic acetylcholine receptor M2 ligand (2R)-1-[(1S)-1-[4-... 10 2
Muscarinic acetylcholine receptor M2 ligand (2R)-4-cyclohexyl-... 12 0
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 4 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 19 11
72 kDa type IV collagenase and Collagenase 3 inhibitor 1-ethyl... 11 5
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 15
Disintegrin and metalloproteinase domain-containing protein 17... 5 2
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 6 1
Disintegrin and metalloproteinase domain-containing protein 17... 12 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 13 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 3 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-[(4-b... 3 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
C-C chemokine receptor type 1 ligand SureCN8184421 family 11 10
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 4 4
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor N-hydro... 3 1
Muscarinic acetylcholine receptor M2 ligand 4-[2-[4-(1,3-benzo... 10 0
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor 3-cyclo... 5 0
Histamine H3 receptor and D(3) dopamine receptor ligand AGN-PC... 1 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074P5J family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397186 CHEMBL371691 Bioactive AGN-PC-075XRL
CFAMM00397192 CHEMBL74117 Bioactive cyclopropyl-[4-[4-[1-[4-(4-methoxyphenyl)sulfonylphenyl]ethenyl]piperidin-1-yl]piperidin-1-yl]methanone
CFAMM00397191 CHEMBL70848 Bioactive AGN-PC-074H5I
CFAMM00397190 CHEMBL72787 Bioactive AGN-PC-074H8I
CFAMM00397189 CHEMBL1951911 Bioactive N-ethyl-N-[1-[(3R)-3-(3-methoxyphenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
CFAMM00397188 CHEMBL305607 Bioactive AGN-PC-074H6Y

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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