CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9680
Family Name Melanin-concentrating hormone receptor 1 and Potassium voltage-gated channel subfamily H member 2 ligand AGN-PC-03OF3K family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00331550 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Menin Binder Superfamily 2
Class Class 3257

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
DNA topoisomerase 2-beta Inhibitor Cinoxacin Family 2 17
Histamine H1 receptor Ligand Tranilast Family 5 125
Endothelin-1 receptor Ligand Atrasentan Family 127 336
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Potassium ... 1 15
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Liver carboxylesterase 1 Inhibitor 5-(trifluoromethoxy)-1h-ind... 3 12
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Multidrug resistance protein 1 and Multidrug resistance-associ... 3 55
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Amine oxidase [flavin-containing] A and Mitogen-activated prot... 1 71
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
Cannabinoid receptor 2 ligand 8-butoxy-N-(2-fluoro-2-phenyleth... 12 7
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 4
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 8... 4 15
Poly [ADP-ribose] polymerase 1 inhibitor 6-[1-(2,3-dihydro-1,4... 1 30
C-C chemokine receptor type 3 ligand 1-(3-cyanophenyl)-3-[6-[[... 2 5
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3... 2 3
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-087THY family 1 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Substance-P receptor ligand AGN-PC-075NSQ family 9 3
Neuropeptide S receptor and Survival motor neuron protein liga... 1 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1589265 family 1 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Mu-type opioid receptor ligand AGN-PC-075GAW family 2 1
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X1U ... 2 3
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
Melanin-concentrating hormone receptor 1 and Potassium voltage... 4 1
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
Integrin beta-3 and Integrin alpha-2 inhibitor 3-(4-methoxyphe... 4 6
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 7
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 11 4
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 13
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
Cholinesterase and Acetylcholinesterase inhibitor [(3aR,8bS)-4... 1 0
Nicotinamide phosphoribosyltransferase inhibitor N-(1,3-benzod... 1 0
Kinesin-like protein KIF11 inhibitor N-(3-aminopropyl)-N-[1-(3... 1 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075HBO ... 2 44
Angiotensin-converting enzyme inhibitor (6aS,8R)-8-hydroxy-5-[... 1 2
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 4-[3... 4 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397221 CHEMBL195255 Bioactive AGN-PC-075X2F
CFAMM00397225 CHEMBL206030 Bioactive SureCN6209684

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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