CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9681
Family Name Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-anilinopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00397237 Functional Category Bioactive
Superfamily Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-protein ligase XIAP Inhibitor SM-131 Superfamily
Class Class 904

Cousin Family NamesSeedsMembers
Leukotriene A-4 hydrolase Inhibitor N5-[4-(n-phenylamino)pheny... 2 3
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 1 1
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 3 3
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
B2 bradykinin receptor ligand AGN-PC-074WA4 family 2 3
Cannabinoid receptor 2 ligand SureCN738026 family 5 68
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 14
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 6
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 3
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
Dipeptidyl peptidase 4 inhibitor SureCN2709139 family 5 7
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 3
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 19b family 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor [(... 2 23
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(5-bromo-2,3-dihyd... 2 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 3 1
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-chlorophenyl... 3 3
Dipeptidyl peptidase 4 inhibitor 4-[4-[(3S,5S)-5-(1,3-thiazoli... 3 2
Histamine H3 receptor and Histamine receptor H3 ligand N-[4-[3... 5 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-nitrophenyl)... 3 0
Histamine receptor H3 ligand N-[4-[3-(2-methylpyrrolidin-1-yl)... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Dipeptidyl peptidase 4 inhibitor 4-[[(3S,5S)-5-[(2S)-2-cyanopy... 4 12
Dipeptidyl peptidase 4 inhibitor (2S,4S)-1-[2-[[1-[4-cyano-2-(... 2 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
E3 ubiquitin-protein ligase XIAP inhibitor (2S)-N-[(2S)-1-[(2S... 1 0
NP Tert-butyl ((s)-3-methyl-1-oxo-1-(4-(((s)-1-oxo-1-(p-tolyla... 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397237 CHEMBL195335 Bioactive (2S)-1-[(2S,4S)-4-anilinopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
CFAMM00397235 CHEMBL371585 Bioactive 1-[(3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]pyrrolidin-3-yl]-3-phenylurea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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