CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9686
Family Name Prothrombin inhibitor N-[[(5R,6R)-2-amino-6-methyl-1,4,5,6-tetrahydropyrimidin-5-yl]methyl]-2-[6-methyl-2-oxo-3-(2-phenylethylamino)pyrazin-1-yl]acetamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00397315 Functional Category Bioactive
Superfamily Coagulation factor X and Potassium voltage-gated channel subfamily H member 2 Ligand RWJ-671818 Superfamily
Class Class 2145

Cousin Family NamesSeedsMembers
Coagulation factor X and Potassium voltage-gated channel subfa... 5 15
Prothrombin and Trypsin-1 inhibitor SureCN7255204 family 3 38
5-hydroxytryptamine receptor 2C ligand 3-methyl-6-[(2R)-2-meth... 2 0
5-hydroxytryptamine receptor 2C ligand 2-[2-(2-chlorophenyl)et... 4 0


External ID

Functional Category

Molecule Name

CFAMM00397313 CHEMBL417635 Bioactive N-[[(5S)-2-amino-1,4,5,6-tetrahydropyrimidin-5-yl]methyl]-2-[6-methyl-2-oxo-3-(2-phenylethylamino)pyrazin-1-yl]acetamide
CFAMM00397315 CHEMBL19548 Bioactive N-[[(5R,6R)-2-amino-6-methyl-1,4,5,6-tetrahydropyrimidin-5-yl]methyl]-2-[6-methyl-2-oxo-3-(2-phenylethylamino)pyrazin-1-yl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



75964 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543