CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9690
Family Name C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-[3-(5-methyltetrazol-1-yl)phenyl]urea family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00397333 Functional Category Bioactive
Superfamily Histamine H4 receptor Ligand A-943931 Superfamily
Class Class 824

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Histamine H1 receptor Ligand Mizolastine Family 14 603
Tyrosine-protein kinase JAK2 Inhibitor INCB18424 Family 3 130
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Histamine H3 receptor ligand SureCN4025673 family 4 2
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 8
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 3
Survival motor neuron protein inhibitor CHEMBL1583999 family 1 3
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 5 0
Corticotropin-releasing factor receptor 1 ligand SureCN6301726... 4 1
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 2 2
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 4 2
Adenosine receptor A1 ligand N-butyl-5-phenyl-3-[[2-(trifluoro... 7 2
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 2 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 1
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 11 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397333 CHEMBL195555 Bioactive 1-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-[3-(5-methyltetrazol-1-yl)phenyl]urea
CFAMM00397332 CHEMBL364068 Bioactive 1-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-[4-(1,2,4-triazol-1-yl)phenyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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