CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9702
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand 2-(4-ethylthiophen-2-yl)-7-methyl-1H-pyrazolo[4,3-c]quinolin-3-one family
No. of Seeds 33 No. of Other Members 5
Family Centroid CFAMM00397450 Functional Category Bioactive
Superfamily GABA theta subunit and Gamma-aminobutyric acid receptor subunit pi Binder Superfamily 6
Class Class 3254

Cousin Family NamesSeedsMembers
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 9 22
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 5
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00CFYH ... 2 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 10 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397447 CHEMBL283556 Bioactive 7-methyl-2-[5-(2-methylpropyl)thiophen-2-yl]-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397461 CHEMBL19735 Bioactive 7-methyl-2-(5-propylthiophen-3-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397427 CHEMBL49361 Bioactive 7-fluoro-2-(5-methylthiophen-3-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397440 CHEMBL299787 Bioactive 6-fluoro-2-(5-methylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397433 CHEMBL277027 Bioactive 7-methyl-2-(5-methylthiophen-3-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397446 CHEMBL50709 Bioactive 2-(5-ethylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397460 CHEMBL49283 Bioactive 7-fluoro-2-(5-methylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397426 CHEMBL277714 Bioactive 7-methyl-2-thiophen-2-yl-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397439 CHEMBL282722 Bioactive 7-methyl-2-(5-methylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397452 CHEMBL20138 Bioactive 2-(5-ethylthiophen-2-yl)-7-methyl-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397432 CHEMBL19867 Bioactive 2-(5-butylthiophen-2-yl)-7-methyl-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397445 CHEMBL19566 Bioactive 7-methyl-2-(5-propan-2-ylthiophen-3-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397459 CHEMBL19572 Bioactive 2-(5-ethylthiophen-3-yl)-7-methyl-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397438 CHEMBL48935 Bioactive 3H-Pyrazolo[4,3-c]quinolin-3-one, 2,5-dihydro-2-(5-methyl-2-thienyl)-
CFAMM00397451 CHEMBL45690 Bioactive 2-(5-ethylthiophen-3-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397431 CHEMBL19963 Bioactive 7-methyl-2-(5-propan-2-ylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397444 CHEMBL47657 Bioactive 6-fluoro-2-(5-methylthiophen-3-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397458 CHEMBL278099 Bioactive 7-methyl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397437 CHEMBL45700 Bioactive 104679-67-6
CFAMM00397450 CHEMBL19817 Bioactive 2-(4-ethylthiophen-2-yl)-7-methyl-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397464 CHEMBL19719 Bioactive 7-methyl-2-(5-propylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397430 CHEMBL299751 Bioactive SureCN10531316
CFAMM00397443 CHEMBL298630 Bioactive 6-methyl-2-(5-methylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397457 CHEMBL49244 Bioactive 2-(4-methylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397436 CHEMBL20361 Bioactive 7-methyl-2-(4-propylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397463 CHEMBL299857 Bioactive CHEBI:173012
CFAMM00397429 CHEMBL277712 Bioactive 7-methyl-2-(4-methylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397456 CHEMBL296628 Bioactive 2-(4,5-dimethylthiophen-2-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397435 CHEMBL50540 Bioactive 2-(4-methylthiophen-3-yl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397448 CHEMBL299371 Bioactive 3H-Pyrazolo[4,3-c]quinolin-3-one, 2,5-dihydro-2-(3-thienyl)-
CFAMM00397462 CHEMBL19736 Bioactive 2-(5-butylthiophen-3-yl)-7-methyl-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397428 CHEMBL19828 Bioactive 7-methyl-2-[5-(2-methylpropyl)thiophen-3-yl]-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00397454 CHEMBL297511 Bioactive 6-methyl-2-(5-methylthiophen-3-yl)-1H-pyrazolo[4,3-c]quinolin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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