CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9709
Family Name Growth hormone secretagogue receptor type 1 and Potassium voltage-gated channel subfamily H member 2 ligand 6-(4-fluorophenoxy)-2-methyl-3-[[(3S)-1-propan-2-ylpiperidin-3-yl]methyl]pyrido[2,3-d]pyrimidin-4-one family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00397519 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily H member 2 and Alpha-1A adrenergic receptor Binder Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Glucokinase Inhibitor GKA1 Family 2 67
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Reverse transcriptase/RNaseH inhibitor AC1LALKM family 2 19
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
Bifunctional epoxide hydrolase 2 inhibitor SureCN3216677 family 4 9
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
Motilin receptor ligand SureCN2765637 family 1 1
Focal adhesion kinase 1 inhibitor 2-[[2-(2-methoxy-4-morpholin... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 2 2
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 6 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Hydroxycarboxylic acid receptor 2 and Hydroxycarboxylic acid r... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397521 CHEMBL1956987 Bioactive 2-methyl-6-(4-phenylphenoxy)-3-[[(3S)-1-propan-2-ylpiperidin-3-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
CFAMM00397520 CHEMBL1956990 Bioactive 6-(4-bromo-2-fluorophenoxy)-2-methyl-3-[[(3S)-1-propan-2-ylpiperidin-3-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
CFAMM00397519 CHEMBL1956989 Bioactive 6-(4-fluorophenoxy)-2-methyl-3-[[(3S)-1-propan-2-ylpiperidin-3-yl]methyl]pyrido[2,3-d]pyrimidin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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