CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9721
Family Name Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-protein ligase XIAP inhibitor methyl 4-[[2-[(3S,6S,7R,9aS)-3-(benzhydrylcarbamoyl)-6-[[(2S)-2-(methylamino)butanoyl]amino]-5-oxo-1,2,3,6,7,8,9,9a-octahydropyrrolo[1,2-a]azepin-7-yl]ethylamino]methyl]benzoate family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00397555 Functional Category Bioactive with Natural Product
Superfamily Proto-oncogene tyrosine-protein kinase Src Inhibitor RU85053 Superfamily
Class Class 923

Cousin Family NamesSeedsMembers
Neutrophil elastase Inhibitor FK-706 Family 8 85
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(4-me... 2 9
Cathepsin B and Cathepsin L1 inhibitor 3-[[(2R)-2-cyano-2-[[(2... 3 4
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Bifunctional epoxide hydrolase 2 inhibitor SureCN4346970 family 6 8
B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[(... 18 17
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 4 0
Neutrophil elastase inhibitor SureCN7273831 family 2 2
Melanin-concentrating hormone receptor 1 ligand N-methyl-N-[(3... 2 2
Neutrophil elastase inhibitor 4-[(E)-3-[[(2S)-3-methyl-1-oxo-1... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397555 CHEMBL1957106 Bioactive methyl 4-[[2-[(3S,6S,7R,9aS)-3-(benzhydrylcarbamoyl)-6-[[(2S)-2-(methylamino)butanoyl]amino]-5-oxo-1,2,3,6,7,8,9,9a-octahydropyrrolo[1,2-a]azepin-7-yl]ethylamino]methyl]benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27760 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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