CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9737
Family Name Renin and Potassium voltage-gated channel subfamily H member 2 ligand N-[2-[2-[4-[(3S,4R)-4-[4-[(2,2-difluoro-3-methoxypropoxy)methyl]phenyl]-4-hydroxypiperidin-3-yl]-3-methylphenyl]phenyl]ethyl]acetamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00397709 Functional Category Bioactive
Superfamily Renin and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 3
Class Class 3563

Cousin Family NamesSeedsMembers
Melanocortin receptor 4 ligand 2-[(1S)-6-chloro-1'-[(3S,4R)-4-... 2 12
Renin and Potassium voltage-gated channel subfamily H member 2... 6 0
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 4 6
C-C chemokine receptor type 5 ligand AC1LAKN8 family 4 5
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 1 0


External ID

Functional Category

Molecule Name

CFAMM00397708 CHEMBL1957795 Bioactive N-[2-[2-[4-[(3S,4R)-4-(3,4-difluorophenyl)-4-hydroxypiperidin-3-yl]-3-methylphenyl]phenyl]ethyl]acetamide
CFAMM00397707 CHEMBL1957797 Bioactive N-[2-[2-[4-[(3S,4R)-4-hydroxy-4-[4-[[(2S)-3-methoxy-2-methylpropoxy]methyl]phenyl]piperidin-3-yl]-3-methylphenyl]phenyl]ethyl]acetamide
CFAMM00397710 CHEMBL1957788 Bioactive N-[2-[2-[4-[(3R,3'S)-5,6-difluorospiro[1H-2-benzofuran-3,4'-piperidine]-3'-yl]-3-methylphenyl]phenyl]ethyl]acetamide
CFAMM00397709 CHEMBL1957789 Bioactive N-[2-[2-[4-[(3S,4R)-4-[4-[(2,2-difluoro-3-methoxypropoxy)methyl]phenyl]-4-hydroxypiperidin-3-yl]-3-methylphenyl]phenyl]ethyl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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