CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9758
Family Name Cell division cycle 7-related protein kinase and Protein DBF4 homolog A inhibitor 2-(cyclohexylamino)-6-pyridin-4-yl-1H-pyrimidin-4-one family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00397855 Functional Category Bioactive
Superfamily CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Amrinone Superfamily
Class Class 11

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Amrino... 3 55
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Transient receptor potential cation channel subfamily V member... 16 295
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Dipeptidyl peptidase 4 Inhibitor Nvp-dpp728 Family 11 42
XL-888 family 16 85
Class II cytokine receptor Ligand IL-10 Family 7 45
Cyclin-dependent kinase 8 Inhibitor Oxindole 94 Family 2 3
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Alpha-1A adrenergic receptor Ligand L-771688 Family 8 14
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Hydroxycarboxylic acid receptor 2 Ligand 2-(6-phenylhexyl)pyri... 4 11
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
Tubulin beta chain Inhibitor 2-m-tolyl-1h-[1,8]naphthyridin-4-... 5 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-cyc... 3 6
Dipeptidyl peptidase 4 inhibitor SureCN3389584 family 2 2
Neuropeptide Y receptor type 5 ligand (5E)-5-[(4S,5S)-4-(4-flu... 18 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 1 1
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 7 2
Transient receptor potential cation channel subfamily V member... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00397855 CHEMBL1958401 Bioactive 2-(cyclohexylamino)-6-pyridin-4-yl-1H-pyrimidin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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