CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9766
Family Name Cathepsin L1 and Cathepsin S inhibitor N-[(2S)-4-methyl-1-oxo-1-[[(4S)-3-oxo-1-pyridin-2-ylsulfonylazepan-4-yl]amino]pentan-2-yl]quinoline-8-carboxamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00396589 Functional Category Bioactive
Superfamily Cathepsin S and Cathepsin L1 Binder Superfamily
Class Class 3305

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Prelamin-A/C and Pyruvate kinase PKM inhibitor CHEMBL1481187 f... 1 7
Cathepsin L1 and Cathepsin S inhibitor N-[(2S)-4-methyl-1-oxo-... 3 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3-fluo... 6 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 6-(b... 5 5
Hepatocyte growth factor receptor and Protein-tyrosine kinase ... 2 15
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 3
B1 bradykinin receptor ligand AGN-PC-00RZQU family 2 0
C-X-C chemokine receptor type 3 ligand AGN-PC-07ZH3V family 1 1
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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