CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9788
Family Name Insulin-like growth factor 1 receptor ligand 3-[[2-[2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]thiophene-2-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00398027 Functional Category Bioactive
Superfamily Tyrosine-protein kinase Lyn and Mitogen-activated protein kinase 9 Binder Superfamily
Class Class 3402

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 3 1
Insulin-like growth factor 1 receptor ligand GSK1220512A family 20 15
Insulin-like growth factor 1 receptor ligand 4-(2,3-dihydroind... 1 0
Focal adhesion kinase 1 inhibitor 2-[[2-(2-methoxy-4-morpholin... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 0
Insulin-like growth factor 1 receptor ligand SureCN310120 family 10 0
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 15 1
Insulin-like growth factor 1 receptor ligand AGN-PC-050GPS family 7 0
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 6 0


External ID

Functional Category

Molecule Name

CFAMM00398027 CHEMBL1964269 Bioactive 3-[[2-[2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]thiophene-2-carboxamide
CFAMM00398026 CHEMBL514718 Bioactive AGN-PC-077MU5

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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