CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9805
Family Name Cell division cycle 7-related protein kinase and Casein kinase II subunit alpha inhibitor N-[5-(1-benzyltriazol-4-yl)-1H-indazol-3-yl]benzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00248588 Functional Category Bioactive
Superfamily Cell division cycle 7-related protein kinase and Dual specificity protein kinase CLK4 Binder Superfamily
Class Class 1024

Cousin Family NamesSeedsMembers
Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Family 8 56
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
PHA848125 family 13 138
PF-4217903 family 14 65
Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazo... 6 62
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
Glycogen synthase kinase-3 beta Inhibitor N-(6-(pyridin-4-yl)-... 4 23
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Glycogen synthase kinase-3 beta Inhibitor N-(6-chloro-5-p-toly... 5 9
Glycogen synthase kinase-3 beta Inhibitor (e)-n-(6-(prop-1-eny... 3 0
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand N-(9h-... 5 2
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 4
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZYJE fa... 15 5
Sphingosine 1-phosphate receptor 1 ligand SureCN3029336 family 4 8
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... 10 10
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... 2 3
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 4 7
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 33
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07ZE3... 6 1
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Mitogen-activated protein kinase kinase kinase kinase 5 and Du... 1 18
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Coagulation factor X and Trypsin-1 inhibitor SureCN3836037 family 5 4
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Glycogen synthase kinase-3 beta and Dual specificity protein k... 4 5
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 4 20
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 2
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 2
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Mitogen-activated protein kinase 14 inhibitor ethyl N-[4-[5-(m... 5 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 10 0
Mast/stem cell growth factor receptor Kit and Receptor-type ty... 8 3
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Calcitonin gene-related peptide type 1 receptor ligand N-[2-(7... 5 3
Melanin-concentrating hormone receptor 1 ligand 6-(4-chlorophe... 8 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... 3 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 6
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 6 0
Metabotropic glutamate receptor 5 ligand 5-(4-fluorophenyl)-1,... 7 1
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Calcitonin gene-related peptide type 1 receptor ligand N-[2-(7... 16 0
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 2 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 2
Tyrosine-protein kinase receptor TYRO3 ligand 3-amino-6-(1H-in... 2 3
P2X purinoceptor 7 inhibitor N-cyano-N'-(2-methylphenyl)-4-[2-... 2 1
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor N-[5-(2,2-di... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43594 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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