CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9809
Family Name 5-hydroxytryptamine receptor 6 ligand SureCN5253197 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00398126 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 Binder Superfamily 3
Class Class 44

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
Melatonin receptor type 1A Ligand Melatonin Family 20 988
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
Apricoxib family 8 77
Indeglitazar family 3 39
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
5-hydroxytryptamine receptor 2A Ligand [2-(6-methoxy-indol-1-y... 2 10
D(2) dopamine receptor Ligand SLV-314 Family 19 69
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Prostaglandin G/H synthase 2 Inhibitor 5-methoxy-2-(4-(methyls... 3 12
Tyrosine-protein kinase SYK and Low affinity immunoglobulin ep... 1 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 6
5-hydroxytryptamine receptor 6 ligand N-[3-[[(2R)-1-methylpyrr... 6 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 5
Cannabinoid receptor 2 ligand AGN-PC-09M5M9 family 1 0
5-hydroxytryptamine receptor 6 ligand SureCN5502542 family 4 2
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 1 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Progesterone receptor and Androgen receptor ligand AGN-PC-04QD... 1 0
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 2 0
Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N... 4 1
5-hydroxytryptamine receptor 6 ligand CHEMBL1950763 family 1 1
5-hydroxytryptamine receptor 6 ligand 9-(4-methoxyphenyl)sulfo... 1 0
5-hydroxytryptamine receptor 6 ligand 1-(2-bromo-4-methoxyphen... 2 1
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 1 3
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 6 ligand 1-[9-(2,5-dimethoxypheny... 2 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-075BWR family 1 1
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Oxytocin receptor and Vasopressin V1a receptor ligand 4-methox... 9 8
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-(1-methyl-4... 14 12
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
DNA-(apurinic or apyrimidinic site) lyase and Alkaline phospha... 1 2
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 1 1
5-hydroxytryptamine receptor 6 ligand SureCN5366229 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00398125 CHEMBL236988 Bioactive AGN-PC-046WXC
CFAMM00398124 CHEMBL371886 Bioactive 1-(3,4-dimethoxyphenyl)sulfonyl-3-[[(2S)-1-methylpyrrolidin-2-yl]methyl]indole
CFAMM00398126 CHEMBL196619 Bioactive SureCN5253197

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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