CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9817
Family Name Caspase-1 and Caspase-8 inhibitor (4S,7S,11aS)-2-(benzenesulfonyl)-N-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-7-(naphthalene-2-carbonylamino)-6-oxo-3,4,7,8,9,10,11,11a-octahydro-1H-pyrazino[1,2-a]azocine-4-carboxamide family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00398160 Functional Category Bioactive
Superfamily Caspase-8 and Caspase-1 Binder Superfamily
Class Class 2026

Cousin Family NamesSeedsMembers
Integrin beta-3 Inhibitor L-709780 Family 9 10
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Caspase-1 and Caspase-8 inhibitor (4S,7S,11aS)-7-benzamido-N-[... 7 18
Caspase-1 and Caspase-8 inhibitor (4S,7S,11aS)-7-benzamido-N-[... 3 0
Caspase-1 and Caspase-8 inhibitor benzyl (4S,7S,9Z,11aS)-7-ben... 2 0
Caspase-1 and Caspase-8 inhibitor (4S,7S,9Z,11aS)-N-[(3S)-2-hy... 2 3
Caspase-1 and Caspase-8 inhibitor N-[(6S)-3-(benzamidomethyl)-... 4 4
Caspase-1 and Caspase-8 inhibitor (4S,7S,11aS)-7-benzamido-4-N... 1 1


External ID

Functional Category

Molecule Name

CFAMM00398162 CHEMBL411759 Bioactive N-[(6S)-3-(benzenesulfonamidomethyl)-1-[2-[[(3S)-2-hydroxy-5-oxooxolan-3-yl]amino]-2-oxoethyl]-7-oxo-5,6-dihydro-2H-azepin-6-yl]naphthalene-2-carboxamide
CFAMM00398160 CHEMBL196761 Bioactive (4S,7S,11aS)-2-(benzenesulfonyl)-N-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-7-(naphthalene-2-carbonylamino)-6-oxo-3,4,7,8,9,10,11,11a-octahydro-1H-pyrazino[1,2-a]azocine-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



80838 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543