CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9856
Family Name Pol polyprotein inhibitor ethyl)-amide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00398395 Functional Category Bioactive
Superfamily Pol polyprotein and Cytochrome P450 3A4 Binder Superfamily
Class Class 3351

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor AC1LARNY family 28 17
Pol polyprotein inhibitor (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5... 12 0
Pol polyprotein and Cytochrome P450 3A4 inhibitor P3 arylpyrro... 19 1
Pol polyprotein inhibitor (2S)-4-[2-[5-(4-fluorophenyl)-1,3-ox... 12 0
Pol polyprotein inhibitor pyridylthiophene analog 10 family 3 0
Pol polyprotein inhibitor pyridylthiophene analog 16 family 4 0
Pol polyprotein inhibitor pyridylfuran analog 14 family 6 0
Beta-3 adrenergic receptor ligand 6-[4-[2-[[(2S)-3-[(3,3-dimet... 6 7
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 1 4


External ID

Functional Category

Molecule Name

CFAMM00398395 CHEMBL372527 Bioactive ethyl)-amide
CFAMM00398394 CHEMBL197114 Bioactive (2S)-4-[[2-(4-fluorophenyl)-1,3-thiazol-4-yl]methyl]-1-[(2S,4S)-2-hydroxy-5-[[(3S,4S)-3-hydroxy-3,4-dihydro-2H-chromen-4-yl]amino]-4-[[5-(4-methylpyridin-3-yl)furan-2-yl]methyl]-5-oxopentyl]-N-(2,2,2-trifluoroethyl)piperazine-2-carboxamide
CFAMM00398393 CHEMBL370179 Bioactive (2S)-4-[[5-(4-chlorophenyl)thiophen-2-yl]methyl]-1-[(2S,4S)-2-hydroxy-5-[[(3S,4S)-3-hydroxy-3,4-dihydro-2H-chromen-4-yl]amino]-4-[[5-(4-methylpyridin-3-yl)furan-2-yl]methyl]-5-oxopentyl]-N-(2,2,2-trifluoroethyl)piperazine-2-carboxamide
CFAMM00398392 CHEMBL78514 Bioactive AC1LARNV

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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