CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9864
Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2B ligand 1-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3-[4-methyl-3-(trifluoromethyl)phenyl]imidazolidin-2-one family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00279895 Functional Category Bioactive
Superfamily Translocator protein and Gonadotropin-releasing hormone receptor Binder Superfamily
Class Class 2417

Cousin Family NamesSeedsMembers
Beta-3 adrenergic receptor Ligand Cgp 12177 Family 3 8
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2I family 3 3
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,... 2 11
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 3
5-hydroxytryptamine receptor 1A ligand AGN-PC-0034EG family 5 2
5-hydroxytryptamine receptor 1A ligand AGN-PC-00FVK4 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00398417 CHEMBL197170 Bioactive 1-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]-3-(3-fluorophenyl)imidazolidin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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