CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9869
Family Name 5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic receptor ligand (E)-but-2-enedioic acid;N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-methylpyrrole-2-carboxamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00291230 Functional Category Bioactive
Superfamily Alpha-1D adrenergic receptor and Inositol monophosphatase 1 Binder Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 28 24
Neutrophil elastase inhibitor phenyl N-[(2S)-1-[(2S)-2-[[(3S)-... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 2
Neuronal acetylcholine receptor subunit alpha-7 ligand 2-[3-cy... 2 5
Vasopressin V1b receptor ligand 2-[3-(3-chlorophenyl)-7-[3-(3-... 8 17
Bifunctional epoxide hydrolase 2 inhibitor SureCN3216677 family 4 9
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Sodium channel protein type 10 subunit alpha and Sodium channe... 3 22
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(2-... 3 3
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 11
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 2 6
Translocator protein inhibitor 2-fluoro-N-[(2-methoxyphenyl)me... 8 27
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 2
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
D(3) dopamine receptor and D(2) dopamine receptor ligand Piper... 3 14
5-hydroxytryptamine receptor 1A and D(4) dopamine receptor lig... 1 0
Motilin receptor ligand SureCN2768193 family 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
Macrophage colony-stimulating factor 1 receptor ligand 4-(2,3-... 12 7
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 1 2
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 6 1
B2 bradykinin receptor ligand 1-N,3-N-dimethyl-4-[methyl-[2-[[... 4 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Cytochrome P450 1A2 and Metabotropic glutamate receptor 4 liga... 1 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00398432 CHEMBL282453 Bioactive N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-methylpyrrole-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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