CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9873
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 1B ligand AGN-PC-075YDL family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00335183 Functional Category Bioactive
Superfamily Monocarboxylate transporter 1 and Cytochrome P450 2C9 Binder Superfamily
Class Class 3370

Cousin Family NamesSeedsMembers
D(3) dopamine receptor Ligand SB-277011 Family 13 178
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 19
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Metabotropic glutamate receptor 1 ligand AGN-PC-046KML family 7 40
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 13 37
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9TG5 family 11 10
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9S6C family 10 1
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00JFFW ... 12 14
Melanin-concentrating hormone receptor 1 ligand 6-(4-chlorophe... 2 0
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 3 4
Metabotropic glutamate receptor 1 ligand SureCN8238697 family 2 0
Metabotropic glutamate receptor 1 ligand SureCN8238239 family 3 0
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[4-oxo-3-(4-p... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 5 1
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 1
Methionine aminopeptidase 1 inhibitor ethyl 4-[4-(2-pyridin-2-... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00398450 CHEMBL438619 Bioactive AGN-PC-075YE6
CFAMM00398449 CHEMBL199443 Bioactive 7-methyl-3-[2-(4-quinolin-8-ylpiperazin-1-yl)ethyl]-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-d]pyrimidin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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