CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9886
Family Name Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-[4-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]sulfonylphenyl]benzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00135062 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 1 Binder Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
DNA Binder Procarbazine Family 8 358
Cathepsin K Inhibitor Odanacatib Family 33 84
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Integrin beta-3 Inhibitor L-750034 Family 7 38
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
C-C chemokine receptor type 2 ligand SureCN2988733 family 14 17
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 5
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 6 7
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
Replication protein E1 inhibitor AC1LAK2U family 3 10
B1 bradykinin receptor ligand SureCN13936521 family 19 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[2-[... 10 5
Poly [ADP-ribose] polymerase 1 inhibitor SureCN2769748 family 1 1
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(benze... 2 2
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
C-C chemokine receptor type 2 ligand AGN-PC-03L0Z6 family 1 1
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
Lethal(3)malignant brain tumor-like protein 3 and Lethal(3)mal... 1 0
Secreted frizzled-related protein 1 and Proto-oncogene Wnt-3 i... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27271 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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