CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9898
Family Name Histamine H3 receptor ligand N-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methyl]pyrimidin-2-amine family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00398560 Functional Category Bioactive
Superfamily MK-6096 Superfamily
Class Class 1305

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand BIIB014 Family 26 92
MK-6096 family 3 69
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 11
Potassium voltage-gated channel subfamily H member 2 and Neuro... 3 4
Histamine H4 receptor and Histamine H3 receptor ligand SureCN6... 17 51
Mitogen-activated protein kinase 14 inhibitor N-(4-aminobutyl)... 1 28
Gonadotropin-releasing hormone receptor ligand AGN-PC-034WF4 f... 8 23
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Metabotropic glutamate receptor 5 ligand AGN-PC-09QLD2 family 1 2
Glucose-dependent insulinotropic receptor and Potassium voltag... 4 0
Histamine H4 receptor ligand 8-fluoro-4-[(3R)-3-(methylamino)p... 6 1
Histamine H3 receptor ligand N-[[2-[2-[(2R)-2-methylpyrrolidin... 7 2
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 5
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
Neuropeptide Y receptor type 5 ligand SureCN2658856 family 6 0
Motilin receptor ligand SureCN13392247 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00398557 CHEMBL363645 Bioactive 5-bromo-N-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methyl]pyrimidin-2-amine
CFAMM00398562 CHEMBL445144 Bioactive 5-ethyl-N-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methyl]pyrimidin-2-amine
CFAMM00398561 CHEMBL197608 Bioactive N-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methyl]pyrimidin-5-amine
CFAMM00398560 CHEMBL372546 Bioactive N-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methyl]pyrimidin-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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