CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9921
Family Name Vascular endothelial growth factor receptor 1 and Receptor-type tyrosine-protein kinase FLT3 ligand CHEMBL2005631 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00168930 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 1 and Binder Superfamily
Class Class 427

Cousin Family NamesSeedsMembers
Aurora kinase A Inhibitor ABT-348 Family 20 49
XL-888 family 16 85
5-hydroxytryptamine receptor Ligand Sl65.0472 Family 2 16
Muscarinic acetylcholine receptor M1 Ligand Bo(15)pz Family 4 5
Vascular endothelial growth factor receptor 2 Ligand 3-(4-amin... 2 5
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(2... 2 20
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 13
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-(4... 3 9
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 8 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 9 1
Coagulation factor X inhibitor AGN-PC-078Y4E family 4 6
Coagulation factor X inhibitor AGN-PC-078Y3A family 4 1
Gonadotropin-releasing hormone receptor ligand 1-[4-[1-[(2,6-d... 8 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 13 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 2 2
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 2 1
Caspase-1 inhibitor (3S)-4-oxo-3-[[6-[[4-(quinoxalin-2-ylamino... 5 6
Melanin-concentrating hormone receptor 1 and Muscarinic acetyl... 8 2
Vascular endothelial growth factor receptor 2 and Vascular end... 4 1
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 5 0
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 2 1
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 1 0
Protein-cysteine N-palmitoyltransferase porcupine inhibitor 2-... 5 2
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Transient receptor potential cation channel subfamily V member... 1 0
Vascular endothelial growth factor receptor 2 ligand Thienopyr... 2 2
Histone deacetylase 1 and Potassium voltage-gated channel subf... 3 2
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Potassium ... 2 1
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 1
Adenosine receptor A1 ligand SureCN1497799 family 2 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 5 1
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 5 0
Calcitonin gene-related peptide type 1 receptor ligand N-(1-me... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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