CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9929
Family Name Sigma non-opioid intracellular receptor 1 ligand AGN-PC-003L8Y family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00398704 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A Ligand 1-(4-bromo-2,5-difluorophenyl)-2-aminopropane Superfamily
Class Class 2899

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Beta adrenergic receptor Ligand Bretylium Family 3 11
Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 10
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 1
5-hydroxytryptamine receptor 2A Ligand 1-(4-bromo-2,5-difluoro... 1 5
5-hydroxytryptamine receptor 2A Ligand 1-(10-bromoanthracen-9-... 2 2
Neuronal acetylcholine receptor subunit alpha-9 ligand 3-(4-br... 2 2
Sigma non-opioid intracellular receptor 1 ligand 2-(3-bromophe... 2 1
Sodium-dependent serotonin transporter and Transporter inhibit... 2 8
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 6
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00398705 CHEMBL281619 Bioactive AGN-PC-003L8X
CFAMM00398704 CHEMBL19802 Bioactive AGN-PC-003L8Y

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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