CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9937
Family Name Prothrombin inhibitor N-[[(5R,6R)-2-amino-6-methyl-1,4,5,6-tetrahydropyrimidin-5-yl]methyl]-2-[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]acetamide family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00398758 Functional Category Bioactive
Superfamily Trypsin Inhibitor CVS-2139 Superfamily
Class Class 2991

Cousin Family NamesSeedsMembers
Trypsin Inhibitor CVS-2139 Family 2 7
Trypsin Inhibitor P1 Argininal Derivative Family 13 36
Neutrophil elastase inhibitor 2-[3-(benzylsulfamoylamino)-2-ox... 5 27
Prothrombin and Trypsin-1 inhibitor AGN-PC-073KRV family 3 4
Prothrombin and Trypsin-1 inhibitor N-[[2-(2-aminoethyl)-5-chl... 3 2
Prothrombin inhibitor ethyl (3S)-3-(benzylsulfonylamino)-1-[2-... 3 1
Prothrombin inhibitor 2-[3-(benzylsulfonylamino)-6-methyl-2-ox... 2 3
Prothrombin and Trypsin-1 inhibitor 2-[3-(benzylsulfonylamino)... 4 3


External ID

Functional Category

Molecule Name

CFAMM00398758 CHEMBL274968 Bioactive N-[[(5R,6R)-2-amino-6-methyl-1,4,5,6-tetrahydropyrimidin-5-yl]methyl]-2-[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]acetamide
CFAMM00398756 CHEMBL19811 Bioactive N-[[(5S)-2-amino-1,4,5,6-tetrahydropyrimidin-5-yl]methyl]-2-[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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