CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9942
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 inhibitor N-(2-Chlorophenyl)cinnamamide family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00249312 Functional Category Bioactive
Superfamily Cruzipain and Bifunctional epoxide hydrolase 2 Binder Superfamily
Class Class 564

Cousin Family NamesSeedsMembers
Benzodiazepine receptor ligand benzodiazepine derivative Fludi... 11 78
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Peroxisome proliferator-activated receptor gamma and Retinoic ... 4 9
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Transient receptor potential cation channel subfamily V member... 6 33
Androgen receptor Ligand 6-n-propyl -4-trifluoromethylquinolin... 29 13
Phospholipase D1 Inhibitor Halopemide Family 17 111
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Cruzipain Inhibitor N1,n4-bis(5-chloro-2-methylphenyl)succinam... 1 5
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 5
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 8 3
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
DNA topoisomerase Inhibitor 6-(3-iodo-phenylamino)-1h-pyrimidi... 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 2
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 14 5
Tankyrase-2 inhibitor 7-(2-chlorophenyl)-4-methyl-1H-quinolin-... 1 1
Muscarinic acetylcholine receptor M1 and Beta-lactamase ligand... 1 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 0
Dihydroorotate dehydrogenase (quinone), mitochondrial and Dihy... 1 8
3-hydroxyacyl-CoA dehydrogenase type-2 and 15-hydroxyprostagla... 2 4
Poly [ADP-ribose] polymerase 2 and Poly [ADP-ribose] polymeras... 1 0
G protein-activated inward rectifier potassium channel 4 and G... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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