CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9961
Family Name Glucocorticoid receptor ligand 1,1,1-trifluoro-2-[(1-methyl-3,4-dihydro-2H-naphthalen-1-yl)methyl]-3-quinolin-4-ylpropan-2-ol family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00398866 Functional Category Bioactive
Superfamily Glucocorticoid receptor and 5-hydroxytryptamine receptor 1D Binder Superfamily
Class Class 2748

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-4 Ligand Varenic... 3 54
Histamine H1 receptor Ligand Pheniramine Family 10 380
Citric Acid family 2 58
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 5 23
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 5 69
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 1 3
Metabotropic glutamate receptor 5 Ligand 5-(2-methylquinolin-7... 4 3
Metabotropic glutamate receptor 5 Ligand 7-m-tolyl-1,6-naphthy... 4 2
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 2 1 2
Glucocorticoid receptor ligand 4-fluoro-2-[5,5,5-trifluoro-4-h... 3 9
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 1 0
Glucocorticoid receptor ligand 1,1,1-trifluoro-2-[(1-methyl-3,... 5 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2
Histamine H3 receptor ligand AGN-PC-09M6FC family 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00398865 CHEMBL198564 Bioactive SureCN6198966
CFAMM00398864 CHEMBL398572 Bioactive 2-[(1-ethyl-3,4-dihydro-2H-naphthalen-1-yl)methyl]-1,1,1-trifluoro-3-quinolin-4-ylpropan-2-ol
CFAMM00398866 CHEMBL237496 Bioactive 1,1,1-trifluoro-2-[(1-methyl-3,4-dihydro-2H-naphthalen-1-yl)methyl]-3-quinolin-4-ylpropan-2-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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