CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Metabotropic glutamate receptor 3 Ligand LY354740 Family
No. of Seeds 7 No. of Other Members 12
Family Centroid CFAMM00134071 Functional Category Clinical Trial Drug
Superfamily Metabotropic glutamate receptor 3 Ligand LY354740 Superfamily
Class Class 894

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 1 1


External ID

Functional Category

Molecule Name

CFAMM00134062 CHEMBL121053 Bioactive SureCN2454643
CFAMM00134060 CHEMBL2381652 Bioactive (1R,2S,4R,5R,6R)-2-amino-4-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
CFAMM00134052 CHEMBL2381644 Bioactive (1S,2S,4R,5R,6S)-2-amino-4-azidobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
CFAMM00134057 CHEMBL2381641 Bioactive (1S,2S,5R,6S)-2-amino-4-methylidenebicyclo[3.1.0]hexane-2,6-dicarboxylic acid
CFAMM00134065 CHEMBL8759 Bioactive Eglumegad
CFAMM00134056 CHEMBL2381640 Bioactive (1S,2S,5R,6R)-2-amino-4-oxobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
CFAMM00134071 DCL000158 Clinical Trial Drug LY354740

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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