CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Motilin receptor Ligand Mitemcinal Family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00134240 Functional Category Clinical Trial Drug
Superfamily outer membrane inhibitor polyene Nystatin, 50S ribosomal subunit inhibitor macrolide Josamycin Superfamily
Class Class 492

Cousin Family NamesSeedsMembers
50S ribosomal subunit inhibitor macrolide antibiotics Erythrom... 5 45
50S ribosomal subunit inhibitor macrolide Azithromycin Family 2 5
50S ribosomal subunit inhibitor macrolide Troleandomycin Family 1 2
50S ribosomal subunit inhibitor macrolide Roxithromycin Family 2 1
50S ribosomal subunit inhibitor macrolide Josamycin Family 6 6


External ID

Functional Category

Molecule Name

CFAMM00134243 CHEMBL1628277 Bioactive (2R,3S,4R,5R,8R,9S,10S,11R,12R)-5-ethyl-11-[(2S,3R,4S,6R)-4-[ethyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-3-hydroxy-9-[(2S,4S,6R)-4-methoxy-4,6-dimethyloxan-2-yl]oxy-2,4,8,10,12,14-hexamethyl-6,15-dioxabicyclo[10.2.1]pentadec-1(14)-en-7-one
CFAMM00134241 CHEMBL1778156 Bioactive mitemcinal
CFAMM00134240 DCL000167 Clinical Trial Drug Mitemcinal
CFAMM00134239 DCL000564 Clinical Trial Drug Mitemcinal fumarate
CFAMM00134242 DNC009987 Investigative Drug ABT-229

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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