CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD108
Family Name Aurora kinase A Inhibitor MLN8054 Family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00134244 Functional Category Clinical Trial Drug
Superfamily Aurora kinase A Inhibitor MLN8054 Superfamily
Class Class 898

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Casein kinase II subunit alpha Inhibitor CX-4945 Family 1 7
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
5-hydroxytryptamine receptor 4 ligand AGN-PC-00GB52 family 5 2
Dihydrofolate reductase inhibitor 2-[[4-carboxy-4-[[4-[(2,4-di... 3 1
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 2-[3-[... 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6i family 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6j family 2 1
Aurora kinase A inhibitor 4-[[4-(2-chloroanilino)pyrimidin-2-y... 1 0
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
C-C chemokine receptor type 5 ligand 4-[[5-[[4-[(5R)-5-(3-chlo... 1 0
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-071H3F fa... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00134244 DCL000169 Clinical Trial Drug MLN8054
CFAMM00134249 DCL000170 Clinical Trial Drug MLN8237

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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