CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 72 kDa type IV collagenase and Interstitial collagenase Inhibitor BB-3644 Family
No. of Seeds 3 No. of Other Members 15
Family Centroid CFAMM00127249 Functional Category Clinical Trial Drug
Superfamily 72 kDa type IV collagenase and Interstitial collagenase Inhibitor BB-3644 Superfamily
Class Class 821

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Dipeptidyl peptidase 4 Inhibitor Nvp-dpp728 Family 11 42
XL-888 family 16 85
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Rho-associated protein kinase 2 and cAMP-dependent protein kin... 2 7
Cathepsin K inhibitor 2,4-dimethylpentan-3-yl N-[(3S)-1-(isoqu... 1 0


External ID

Functional Category

Molecule Name

CFAMM00127252 CHEMBL111262 Bioactive (3S)-3-[formyl(hydroxy)amino]-4-methyl-N-[(2S,3S)-3-methyl-1-oxo-1-(pyridin-2-ylamino)pentan-2-yl]-2-(2-methylpropyl)pentanamide
CFAMM00127249 DCL000014 Clinical Trial Drug BB-3644
CFAMM00127238 DNC000079 Investigative Drug 5-carboxymethylthio-3-(3'-chlorophenyl)-1,2,4-oxadiazol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



72521 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543