CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Nitric oxide synthase, brain Inhibitor NXN-188 Family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00134931 Functional Category Clinical Trial Drug
Superfamily Nitric oxide synthase, brain Inhibitor NXN-188 Superfamily
Class Class 904

Cousin Family NamesSeedsMembers
Motilin receptor Ligand GSK962040 Family 30 457
Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family 7 45
Matrix metalloproteinase-9 Inhibitor Ro 28-2653 Family 2 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
Somatostatin receptor type 1 ligand AGN-PC-078XL6 family 9 9
Interstitial collagenase and Matrix metalloproteinase-9 inhibi... 2 2
Prothrombin and Coagulation factor X inhibitor AC1NDIV9 family 1 0
NP (1's,3's,3a's,6a'r)-3'-methyl-5'-(2-methyl-5-nitrophenyl)-3... 4 0


External ID

Functional Category

Molecule Name

CFAMM00134931 DCL000182 Clinical Trial Drug NXN-188

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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