CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin E2 receptor EP4 subtype Ligand ONO-4819 Family
No. of Seeds 11 No. of Other Members 16
Family Centroid CFAMM00135292 Functional Category Clinical Trial Drug
Superfamily Prostaglandin E2 receptor EP4 subtype Ligand ONO-4819 Superfamily
Class Class 907

Cousin Family NamesSeedsMembers
Prostaglandin F2-alpha receptor Ligand Latanoprost Family 4 18
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 3 0
Thromboxane A2 receptor ligand (Z)-7-[3-[(E,3R,4S)-3-hydroxy-4... 1 7
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 2 1
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 2 0


External ID

Functional Category

Molecule Name

CFAMM00135286 CHEMBL64338 Bioactive 2-[3-[(1R,2S,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-4-[3-(methylsulfanylmethyl)phenyl]but-1-enyl]-5-oxocyclopentyl]sulfanylpropylsulfanyl]acetic acid
CFAMM00135279 CHEMBL62779 Bioactive 2-[3-[(1R,2S,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-4-[3-(2-methoxyethyl)phenyl]but-1-enyl]-5-oxocyclopentyl]sulfanylpropylsulfanyl]acetic acid
CFAMM00135278 CHEMBL439934 Bioactive (E)-7-[(1R,2R,3R,5R)-5-fluoro-3-hydroxy-2-[(E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl]cyclopentyl]hept-5-enoic acid
CFAMM00135297 CHEMBL293856 Bioactive SureCN3683053
CFAMM00135290 CHEMBL293647 Bioactive SureCN3689863
CFAMM00135283 CHEMBL305568 Bioactive 2-[3-[(1R,2S,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-4-(3-methylphenyl)but-1-enyl]-5-oxocyclopentyl]sulfanylpropylsulfanyl]acetic acid
CFAMM00135289 CHEMBL292717 Bioactive 2-[3-[(1R,2S,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-4-[3-(propoxymethyl)phenyl]but-1-enyl]-5-oxocyclopentyl]sulfanylpropylsulfanyl]acetic acid
CFAMM00135282 CHEMBL64557 Bioactive 2-[3-[(1R,2S,3R)-2-[(E,3S)-4-[3-(ethoxymethyl)phenyl]-3-hydroxybut-1-enyl]-3-hydroxy-5-oxocyclopentyl]sulfanylpropylsulfanyl]acetic acid
CFAMM00135281 CHEMBL1929528 Bioactive 4-[2-[(1R,2R)-2-[(E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]butanoic acid
CFAMM00135300 CHEMBL292964 Bioactive SureCN2306273
CFAMM00135292 DCL000190 Clinical Trial Drug ONO-4819

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



24319 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543