CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD130
Family Name Vascular endothelial growth factor Inhibitor PTC299 Family
No. of Seeds 6 No. of Other Members 145
Family Centroid CFAMM00137523 Functional Category Clinical Trial Drug with Natural Product
Superfamily Vascular endothelial growth factor Inhibitor PTC299 Superfamily
Class Class 914

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
5-hydroxytryptamine receptor 1D Ligand Rizatriptan Family 7 460
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Benzodiazepine receptor Ligand Midazolam Family 5 160
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Toll-like receptor 7 Ligand Imiquimod Family 3 237
Histamine H1 receptor Ligand Emedastine Family 5 115
Histamine H1 receptor Ligand Mizolastine Family 14 603
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Transient receptor potential cation channel subfamily V member... 15 457
Transient receptor potential cation channel subfamily V member... 6 66
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
Reverse transcriptase Inhibitor Dapivirine Family 5 72
Translocator protein Inhibitor Emapunil Family 7 89
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
HCV NS4B protein Inhibitor Clemizole Family 2 43
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
Tryptase Inhibitor Babim Family 12 90
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Farnesyl pyrophosphate synthase Inhibitor Minodronate Family 1 0
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... 2 7
Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... 2 12
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
Histamine H3 receptor Ligand SCH79687 Family 11 29
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(1-(4-thi... 3 36
Carbonic anhydrase 2 Inhibitor Cyanamide Family 2 32
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Thromboxane-A synthase Inhibitor CGS-13080 Family 3 19
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... 3 18
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Aromatase and Thromboxane-A synthase Inhibitor 6-(1h-imidazol-... 3 8
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 3 2
Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... 7 12
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 1 9
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Metabotropic glutamate receptor 5 Ligand 2-m-tolyl-1,8-naphthy... 7 11
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(4-e... 2 5
Adenosine receptor A3 Ligand 2-(4-nitro-1h-benzo[d]imidazol-2-... 2 12
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Mitogen-activated protein kinase kinase kinase 8 and Stromelys... 6 53
Fatty-acid amide hydrolase 1 Inhibitor JNJ-1661010 Family 3 14
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
Aromatase Inhibitor NSC-356781 Family 3 10
Macrophage migration inhibitory factor Inhibitor 4-iodo-6-phen... 5 4
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
Histamine H4 receptor Ligand A-943931 Family 14 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Farnesyl pyrophosphate synthase Inhibitor [2-(benzoimidazol-1-... 2 16
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Hepatocyte growth factor receptor Ligand 1-benzyl-1h-pyrrolo[3... 2 16
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 6 6
Cytochrome P450 11B1, mitochondrial Inhibitor Methyl 3-(1-benz... 3 12
Cytochrome P450 11B1, mitochondrial Inhibitor 3-(1-benzyl-1h-i... 3 5
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 2 1
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 1 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 9 16
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 2 8
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand N-(9h-... 5 2
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Reverse transcriptase Inhibitor PT-109 Family 6 7
Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... 6 3
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
NADH-ubiquinone oxidoreductase chain 3 Inhibitor 6-thiophen-3-... 2 0
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 14 4
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 2 3
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 7 3
Corticotropin-releasing factor receptor 1 ligand SureCN5395386... 6 5
Potassium voltage-gated channel subfamily H member 2 and Neuro... 2 3
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 9
Corticotropin-releasing factor receptor 1 ligand N-(cyclopropy... 2 10
Bombesin receptor subtype-3 ligand (2R)-1-[4-[2-[5-(2,2-dimeth... 1 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 12
Thromboxane-A synthase inhibitor AGN-PC-00N7V2 family 3 6
Sterol O-acyltransferase 1 inhibitor 1-(2,4-difluorophenyl)-3-... 8 90
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 7
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Platelet-activating factor receptor ligand AGN-PC-0750SP family 4 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 1 2
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Polycystin-2 and Serine/threonine-protein kinase D1 inhibitor ... 4 12
Histamine H3 receptor ligand SureCN4025673 family 4 2
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 1 6
Histamine H3 receptor ligand SureCN4018269 family 1 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 7 6
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 1 0
Mitogen-activated protein kinase 14 inhibitor (E)-3-(2,6-dichl... 1 1
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 3 11
Casein kinase I isoform delta and Mitogen-activated protein ki... 3 18
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Nociceptin receptor and Kappa-type opioid receptor ligand 1-[1... 4 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 2 2
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 5 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 5 2
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 15 3
Glycogen synthase kinase-3 beta and Dual specificity protein k... 4 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Signal transducer and activator of transcription 6 inhibitor A... 3 0
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... 2 2
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(1H-pyr... 2 8
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Metabotropic glutamate receptor 5 ligand AGN-PC-075GBZ family 2 5
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 4 ... 2 1
Progesterone receptor ligand AGN-PC-00B9AT family 4 4
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloropheny... 4 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Cell division cycle 7-related protein kinase and Protein DBF4 ... 15 7
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 11 3
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 0
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 1
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Somatostatin receptor type 3 and Potassium voltage-gated chann... 3 0
Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... 2 2
D(4) dopamine receptor and Alpha-1D adrenergic receptor ligand... 3 3
Transient receptor potential cation channel subfamily V member... 4 0
D(4) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 0
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152398 family 16 1
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 3 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 3 4
Metabotropic glutamate receptor 2 ligand 3-(cyclopropylmethyl)... 1 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... 5 3
Somatostatin receptor type 3 and Potassium voltage-gated chann... 3 3
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206614 family 2 0
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
CGMP-dependent protein kinase inhibitor 1-[2-(4-fluorophenyl)-... 1 4
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Tyrosine-protein kinase JAK1 and Aurora kinase A inhibitor CHE... 2 0
Protein kinase C theta type and Protein kinase C delta type in... 9 0
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Dipeptidyl peptidase 4 and Seprase inhibitor (1S,5S)-5-[3-(tri... 1 0
Motilin receptor ligand SureCN2004322 family 2 1
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 4 4
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Methionine aminopeptidase 2 inhibitor SureCN5373581 family 6 0
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Cathepsin K inhibitor SureCN4141224 family 3 0
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
Androgen receptor ligand AGN-PC-009ZOP family 3 3
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... 2 1
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 5 0
Nociceptin receptor and Potassium voltage-gated channel subfam... 5 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 0
Histamine H3 receptor ligand 2-pyrimidin-5-yl-4-[4-(2-pyrrolid... 1 0
Cathepsin K inhibitor 4-[2,2-dimethylpropyl-[[4-(1,2,4-triazol... 2 1
LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-(3-cyanophenyl)-... 4 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 1 0
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 1 0
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... 3 0
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 2 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00FF1P... 1 3
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor ... 3 0
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 3 0
Mitogen-activated protein kinase 14 inhibitor SureCN828349 family 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor ... 1 0
Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family 2 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand 2-(3-ch... 2 0
Gonadotropin-releasing hormone receptor ligand AGN-PC-00AWCA f... 1 0
5-hydroxytryptamine receptor 3A ligand AGN-PC-077D8K family 3 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Progesterone receptor and Cytochrome P450 2C19 ligand AGN-PC-0... 8 3
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0
Cannabinoid receptor 1 ligand AGN-PC-07CPJ5 family 9 14
Neuropeptide Y receptor type 5 ligand AGN-PC-01NS1A family 7 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Histamine H3 receptor ligand 5-(3-bromophenyl)-2-[2-(1H-imidaz... 2 2
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 5
Reverse transcriptase/RNaseH inhibitor 181305-52-2 family 1 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-00FW8Y family 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 1 1
Reverse transcriptase/RNaseH inhibitor AC1LAPCG family 2 1
Acyl-CoA:cholesterol acyltransferase and Sterol O-acyltransfer... 3 2
D(2) dopamine receptor and D(4) dopamine receptor ligand 3-[1-... 1 0
Cyclin-dependent kinase 1 inhibitor AGN-PC-075VN4 family 1 0
Reverse transcriptase/RNaseH inhibitor AC1LAPCM family 2 0
Reverse transcriptase/RNaseH inhibitor AC1LAPBJ family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name
CFAMM00137523 DCL000203 Clinical Trial Drug PTC299
CFAMM00137559 DNC012677 Investigative Drug 5-(2-Imidazol-1-yl-ethyl)-7,8-dihydro-quinoline
CFAMM00137444 DNC008692 Investigative Drug 5-((1H-imidazol-1-yl)methyl)-7,8-dihydroquinoline
CFAMM00137464 DNC004075 Investigative Drug ML-3375
CFAMM00137405 DNC010506 Investigative Drug 1-(4-Fluorobenzyl)-5-phenyl-1H-imidazole
CFAMM00137415 DNC007141 Investigative Drug SB-216995

Statistics of CFAM Database
 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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