CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD133
Family Name Integrin beta-1 Inhibitor R411 Family
No. of Seeds 33 No. of Other Members 44
Family Centroid CFAMM00137629 Functional Category Clinical Trial Drug
Superfamily Integrin beta-1 Inhibitor R411 Superfamily
Class Class 917

Cousin Family NamesSeedsMembers
Glycine receptor subunit beta Ligand Gw 468816 Family 4 67
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor L-750034 Family 7 38
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 3 18
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Integrin beta-1 and Integrin alpha-4 inhibitor (E)-3-[4-[(2,6-... 3 1
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 1
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 7 3
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5100354 f... 1 1
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6823871 f... 9 0
Integrin alpha-4 and Integrin beta-7 inhibitor (2S)-2-[(2,6-di... 9 27
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2,6-di... 2 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[1-[2-(... 12 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(4-brom... 2 0
Glycogen phosphorylase, liver form inhibitor AGN-PC-00CDLB family 2 0
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 1 0
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00137632 CHEMBL310788 Bioactive SureCN6629363
CFAMM00137625 CHEMBL309222 Bioactive (2S)-2-[(2-bromo-6-methylbenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137602 CHEMBL84802 Bioactive (2S)-2-[(2-chloro-3-methylbenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137665 CHEMBL419279 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(2-methyl-6-propylbenzoyl)amino]propanoic acid
CFAMM00137631 CHEMBL83785 Bioactive SureCN6828409
CFAMM00137658 CHEMBL83031 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-(4-hydroxybutyl)cyclopentanecarbonyl]amino]propanoic acid
CFAMM00137611 CHEMBL84325 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-(2-morpholin-4-ylethyl)cyclopentanecarbonyl]amino]propanoic acid
CFAMM00137651 CHEMBL85375 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(2,6-difluorobenzoyl)amino]propanoic acid
CFAMM00137644 CHEMBL79844 Bioactive (2S)-2-[[1-[(2-chlorophenyl)methyl]cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137657 CHEMBL81610 Bioactive (2S)-2-[(1-but-3-enylcyclopentanecarbonyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137609 CHEMBL31874 Bioactive (2S)-2-[[(2R)-1-benzyl-5-oxopyrrolidine-2-carbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137623 CHEMBL79905 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-(methoxymethyl)cyclopentanecarbonyl]amino]propanoic acid
CFAMM00137636 CHEMBL419666 Bioactive SureCN6626685
CFAMM00137650 CHEMBL83911 Bioactive (2S)-2-[(2-tert-butylbenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137663 CHEMBL79343 Bioactive (2S)-2-[(1-butylcyclopentanecarbonyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137622 CHEMBL83710 Bioactive (2S)-2-[(2-acetyl-6-chlorobenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137599 CHEMBL309320 Bioactive (2S)-2-[[1-(4-acetamidobutyl)cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137649 CHEMBL83856 Bioactive (2S)-2-[[1-(2-acetamidoethyl)cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137662 CHEMBL83424 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(2-methyl-6-propan-2-ylbenzoyl)amino]propanoic acid
CFAMM00137615 CHEMBL312856 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-(4-methoxybutyl)cyclopentanecarbonyl]amino]propanoic acid
CFAMM00137675 CHEMBL313242 Bioactive SureCN6627822
CFAMM00137628 CHEMBL84352 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-[2-(dimethylamino)ethyl]cyclopentanecarbonyl]amino]propanoic acid
CFAMM00137655 CHEMBL48103 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(1-phenylcyclopentanecarbonyl)amino]propanoic acid
CFAMM00137607 CHEMBL79441 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(2-fluoro-6-methylbenzoyl)amino]propanoic acid
CFAMM00137621 CHEMBL79625 Bioactive (2S)-2-[(2,3-dichlorobenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137627 CHEMBL131284 Bioactive (2S)-2-[[(2S)-1-benzyl-5-oxopyrrolidine-2-carbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137667 CHEMBL81989 Bioactive SureCN6627446
CFAMM00137620 CHEMBL83657 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-(2-methoxyethyl)cyclobutanecarbonyl]amino]propanoic acid
CFAMM00137660 CHEMBL81993 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[2-fluoro-6-(trifluoromethyl)benzoyl]amino]propanoic acid
CFAMM00137626 CHEMBL162940 Bioactive (2S)-2-[(1-benzyl-5-oxopyrrolidine-2-carbonyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00137653 CHEMBL45185 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(2,6-dimethylbenzoyl)amino]propanoic acid
CFAMM00137629 DCL000209 Clinical Trial Drug R411

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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